The RX 350 and RX 350h are offered with four trim levels: Base, Premium, Premium Plus, Luxury and F Sport Design. The 450h+ is available with the Luxury trim while the RX 500h is offered in the F Sport Performance trim.
The base model includes paddle shifters, power liftgate, reverse tilt-down heated mirrors, 19-inch aluminum wheels, 8 airbags, auto-dimming rearview mirror, 8-way heated power front seats, leatherette upholstery, cargo cover, dual-zone automatic climate control with separate rear controls, satellite radio, 12-speaker audio system, Apple CarPlay and Android Auto integration, a 9.8-inch touchscreen, 6 USB ports, proximity keyless entry with push-button start, remote start, vehicle tracking system, leather-wrapped steering wheel with power tilting and telescoping adjustment, power windows with one-touch operation, and rain-sensing wipers.
The RX 500h F Sport Performance enhances the driving experience with an auto-leveling suspension, 21-inch wheels, heated and ventilated front bucket seats, sport pedals, an auto tilt-away power sport steering wheel, a 12.3-inch configurable digital gauge cluster, and a 14-inch touchscreen display.
Available safety features across all models include the Lexus Safety System+, a Pre-Collision system with automated braking and pedestrian detection, rear collision warning, driver attention alert, traffic sign recognition, Lane Departure Alert with steering assist, Vehicle Sway Warning, a rear-view camera, All-Speed Dynamic Radar Cruise Control with traffic stop-go functionality, and Intelligent High Beam automatic LED headlights.
The RX 450h+ plug-in hybrid achieves an estimated 35 MPG combined and features a lithium-ion battery for extended electric driving capability.
The 350h hybrid delivers an impressive 36 MPG combined, while the standard RX 350 manages 25 MPG combined in front-wheel drive configuration and 24 MPG with all-wheel drive. The performance-oriented RX 500h provides a respectable 27 MPG combined despite its enhanced power output.
Performance capabilities vary by powertrain, with the RX 500h F Sport Performance achieving the quickest acceleration at 5.9 seconds from 0-60 mph, followed by the RX 450h+ at 6.2 seconds. The RX 350 with all-wheel drive reaches 60 mph in 7.2 seconds, with the 350h completing the sprint in 7.4 seconds.
Every 2025 RX model comes standard with the comprehensive Lexus Safety System+ 3.0, wireless Apple CarPlay and Android Auto integration, and connected services including Safety Connect, Service Connect, and Remote Connect with multi-year trial periods.